Alexis Howerton On Starting Up From New Science

Source: Life Science Leader
By Wayne Koberstein, Executive Editor, Life Science Leader magazine

It is not often I meet my interview subject in the elevator on the way to our meeting room. By the time we get to the right floor, Alexis Howerton, the founding CEO of Spruce Biosciences, has recognized me from a photo and introduced herself, and we have already started the conversation. Our meeting was set only a day or so before we both attended this industry event, and I come knowing next to nothing about Spruce or its lead drug candidate, SPR001, now in midstage development for treating congenital adrenal hyperplasia (CAH).

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Rare Disease Report: Spruce Launches CAH Natural History Study

Yesterday, in observance of Rare Disease Day, Spruce Biosciences announced the launch of the CAH Natural History Study, an initiative to advance knowledge and awareness of congenital adrenal hyperplasia (CAH).

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Rare Daily by Global Genes: Spruce Begins Natural History Study of Rare Endocrine Disorder CAH

Spruce Biosciences said it has launched a natural history study of congenital adrenal hyperplasia, or CAH, a rare endocrine disorder caused by genetic mutations resulting in the inability to produce the critical stress hormone cortisol.

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Spruce Biosciences Receives FDA Orphan Drug Designation for SPR001 for the Treatment of Congenital Adrenal Hyperplasia

Clinical-stage biotech granted orphan drug designation for the treatment of CAH, a rare endocrine disease.

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Spruce Receives Orphan Drug Designation for Treatment of Endocrine Disease

The U.S. Food and Drug Administration (FDA) has granted Orphan Drug Designation to SPR001, a novel therapy being developed by Spruce Biosciences for the potential treatment of congenital adrenal hyperplasia (CAH).

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Rare Endocrine Play Spruce Emerges From Stealth

Spruce Biosciences Inc. (San Francisco, Calif.) revealed a $20 million series A round of funding and said it has begun enrolling patients in a U.S. Phase…

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Rare Endocrine Play Spruce Emerges From Stealth And Announces $20m Series A

Spruce Biosciences Inc. (San Francisco, Calif.) revealed a $20 million series A round of funding and said it has begun enrolling patients in a U.S. Phase…

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Rare Endocrine Play Spruce Emerges From Stealth And Announces $20m Series A

Spruce Biosciences Inc. (San Francisco, Calif.) revealed a $20 million series A round of funding and said it has begun enrolling patients in a U.S. Phase…

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Sprucely Debut

Why spruce believes $20 million series a could take it to pivotal testing

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‘Sprucing’ up the place: $20M series A takes lead asset into phase II in CAH

Spruce Biosciences Inc. landed a $20 million series A last year but kept the financing under wraps, waiting for its only asset, SPR-001, to achieve its first clinical milestone. With a phase II study now testing the small molecule in adults with congenital adrenal hyperplasia (CAH), the San Francisco-based company opted to shed a bit of light on its strategy.

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Up and down the ladder: The latest comings and goings

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Spruce Biosciences Grabs $20 Million to Tackle Genetic Disease

Company focusing on rare endocrine conditions testing drug in mid-stage clinical studies

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Finance Watch: J&J Notes JLabs Incubators’ Success Stories To Date

Life science firms in J&J’s JLabs incubators have raised $9.4bn to date from deals and financings, including five IPOs. Also, October brings a wide range of new equity and VC financings.

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Spruce Biosciences is a clinical-stage biotechnology company developing novel therapies for rare endocrine disorders. We are leveraging our extensive expertise in endocrinology and orphan drug development to meet the significant unmet need of patients suffering from these diseases. We are committed to transforming the quality of life for patients who have been underserved by scientific innovation.